Revulsion
is the natural response to excess. At Yale, Penn, and Stanford, enough officials
apparently succumbed to the revulsion of seeing their doctors and students looking
like walking billboards for the drug industry. For years, patients have
felt the same queasiness at the image of their doctors toting pens, pads, and
tools emblazoned with drug company logos. When patients enter doctors' offices
wallpapered with drug-company posters, they know they will not be hearing much
about natural therapies. And yet doctors complain when they are called pill-pushers.
Other
universities are also going "pharm-free." At the University of
California, Davis, a ban on drug-company gifts takes effect this summer.
UCLA is expected to follow.
"These
are reputable, world-class universities," said Dr. Casey KirkHart, who has refused
drug company giveaways since early in medical school. "There's a real culture
change happening. We're going to wean ourselves off drug money.1"
And
what a load of money it is! Approximately 90 percent of the drug industry's
marketing budget -- $21 billion -- goes to doctors. It is a big investment,
and it has paid off handsomely. Studies have proven again and again that
drug company gifts influence doctors' decisions when prescribing medications.
Even
small gifts and modest meals have influence. A study published in 2003 demonstrated
that the more doctors interacted with drug marketers, the more often they prescribed
expensive drugs even though low-cost generics would do.2 One
of the authors, Dr. Arthur Caplan, director of the University of Pennsylvania's
Center for Bioethics, commented, "It was indisputable that small gifts had tremendous
power in influencing favorable attitudes toward products.1"
A
small gift can affect a doctor's decision-making as much as an all-expenses paid
trip. "With a big gift, you're on guard right away," Dr. Caplan explained.
"The very act of giving a small gift creates a cultural sense of obligation.
Yet it is subtle. Your guard isn't up."
Less
subtle are the young, attractive drug company sales representatives, who do not
frequent doctors' offices to simply adorn the waiting rooms. Their goal
is get doctors to push more product, and higher sales equal bonuses for many reps.
Yet their methods are subtle. There is no hard sell. Reps know that
they only need to sew a friendly, collegial relationship, and by bringing studies,
drug samples, or pizza for lunch, a sense of reciprocity will develop.
Students
Make a Difference Medical students have provided much needed
impetus for the pharm-free movement. In 2002, the American Medical Student
Assn, an independent organization, launched an ongoing pharm-free campaign.
Members agreed to refuse money, gifts, and information from the drug industry.
Instead, they agreed to seek unbiased scientific information on their own. The
group also provided medical students with "No Free Lunch" pens in exchange for
their drug-company logo pens.
Will
Other Medical Institutions Go Pharm-Free? The pharm-free movement
hasn't grown without opposition. Some doctors insist it is their right to
accept drug company gifts, and they can do so without being influenced by the
drug industry. Others argue that free drug samples are helpful for starting
people on new medications, especially those without insurance.
The
downside is that free samples inevitably lead to the use of expensive medications
when older, less expensive, better-known drugs might do. And instead of
drug samples, medical institutions can provide discount pharmacy coupons for low-income
patients.3
Some
medical schools have resisted imposing restrictions on drug company gifting because
of concerns about retaliation by the drug industry. Dr. David Rothman, an
author of a 2006 article on conflicts of interest between doctors and the drug
industry, does not believe the industry will retaliate. "Did the drug companies
stop giving Penn research money? I don't for a minute believe that is going
to happen.4"
Overall,
there are few cogent arguments against adopting a pharm-free stance. The
only question is whether enough doctors and officials feel strongly enough to
go pharm-free at their institutions. We will learn a lot about the current
ethics of the medical community when the final tally of pharm-free vs. pharm-friendly
institutions is taken.
Is
Being Pharm-Free Enough? The pharmaceutical industry is resourceful.
It has many ways of influencing doctors, controlling the information they receive,
and motivating doctors to push their products.
Today,
the pharmaceutical industry exerts tremendous influence over the content of doctors'
continuing education. The drug industry's presence at some medical conferences
is so pervasive, sometimes it is hard to tell whether the conferences are medical
meetings or pharmaceutical industry advertising conventions.
The
pharm-free movement will not prevent a drug company from sending doctors to lavish
resorts. There, doctors will hear from experts that are hand picked for
their willing promotion of the company's medications.
Most
worrisome, drug companies will continue to use the medical journals as conduits
for pushing products and obtaining free coverage in the media. The medical
journals were once the repository of scientific thought and research. Now,
the medical journals are having difficulty ensuring the accuracy and objectivity
of many drug company studies that are published. Medical journals have few
tools to prevent the manipulation of data. They have no way of preventing
the omission of negative results. Efforts to ensure full disclosure by authors
have been disappointing. The science of medicine relies on the integrity
of information published in medical journals. But for drug companies, the
medical journals serve another purpose: extolling the virtues while minimizing
the risks of their drugs. As an example, please see my recent articles on
maximum-dose Lipitor.
Pharm-free
or not, all of these excesses will continue.
You
Can Help I support the pharm-free movement. The reformers
are making progress. Yet there is a long way to go, and the question remains
whether the larger medical community will ever become pharm-free.
You
can help. If your doctor uses drug company giveaways, bring a stack of writing
pads and inexpensive pens to your next office visit. If your doctor asks
why you are giving these to him, smile and say, "It just looks better."
Your doctor will get the point. Be nice about it. It's tough for anyone
to turn down a freebie. Doctors are no different. At the same time,
doctors' first allegiance is supposed to be to their patients. A word from
a patient can have a lot of influence.
References 1. Engel M. A pox on drug maker freebies, say some doctors.
Los Angeles Times, Feb. 4, 2007:A1. 2. Katz D, Caplan AL, Merz JF.
All gifts large and small: toward an understanding of the ethics of the pharmaceutical
industry gift-giving. American Journal of Bioethics 2003;3(3):39-46.
3. Brennan TA, Rothman DJ, et al. Health industry practices that create
conflicts of interest: a policy proposal for academic medical centers. JAMA
2006;295(4):429-433. 4. Saul S. Doctors and drug makers: a move
to end cozy ties. New York Times, Feb. 12, 2007:www.nytimes.com.
__________
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