New
obesity treatment program to sustain weight loss, UCSF study finds
An
obesity treatment that avoids restrictive diets and weight loss
drugs, but instead focuses on training individuals in developing
two fundamental internal skills, has resulted in weight loss that
was sustained for six years, according to a new University of California,
San Francisco study. "This is the first report of a non-surgical
obesity intervention to demonstrate continued weight loss after
treatment ends," said Laurel Mellin, MA, RD, UCSF associate
clinical professor of family and community medicine and pediatrics
and the study's principal investigator. "In contrast to traditional
methods of weight loss that trigger short-term weight loss followed
by rapid weight regain, subjects in this study kept the weight off
even six years later." Mellin will present these findings at
the annual meeting of the American Dietetic Association in Denver
today (October 17).
The
national obesity epidemic, first recognized last year when new data
published in the Journal of the American Medical Association showed
a 49 percent increase in obesity rates since 1991, has intensified
scientific interest in treatments demonstrating long term effectiveness,
Mellin said. According to that report, obesity causes an estimated
280,000 deaths annually and diseases associated with overweight
account for 6.8 percent of U.S. health care costs.
The
intervention, called the Solution Method, teaches the developmental
skills of self nurturing and effective limit setting. The skills
are taught and practiced repeatedly in therapy until the participants
use them automatically. "Our earlier research suggested that
once the skills became integrated, a trend toward persistent emotional
and behavioral balance followed," Mellin said. "Participants
reported eating less not because they were complying with a diet
but because they stopped wanting the extra food."
The
research analyzed data on 27 obese participants in the group program
conducted at UCSF, 19 of who were available for follow-up for six
years. Investigators tracked their weight, blood pressure, exercise,
depression and functioning. The group members participated in 18
weekly two-hour group sessions to practice the developmental skills,
completed journal homework and made telephone "connections"
with other group members for skill practice.
Each
developmental skill involves asking oneself two sets of questions,
Mellin said. The self-nurturing skill questions are: "How do
I feel? What do I need? Do I need support?" The limit-setting
questions are: "Are my expectations reasonable? Is my thinking
positive and powerful? What is the essential pain and the earned
reward?" The skills are designed to internalize responsive
self-parenting and to create emotional balance. When one is emotionally
balanced, then he or she is less likely to go to excess, Mellin
said.
"With
modern day stresses and so much deprivation and chaos in our lives,
most of us need higher levels of these internal skills than our
ancestors needed," she said. "Without the skill to access
a nurturing, secure inner life, we may be at greater risk of emotional
distress and of experiencing common excessive appetites, such as
overeating, overworking or overdrinking," Mellin said. On average,
the participants:
· Lost weight without restrictive diets or weight loss drugs,
averaging 13 pounds in the first 12 weeks of training. ·
Continued to lose weight after the treatment ended and continued
to lose weight at six years. · Maintained a weight loss averaging
17 pounds for the entire group and 23 pounds for those who demonstrated
mastery of the skills at the end of the treatment. · Decreased
depression scores by 60 percent at 12 weeks and by 80 percent at
six years. · Increased exercise from an average of 110 minutes
weekly at the beginning of the study to a weekly average of 247
minutes at 12 weeks and 240 minutes at six years. · Decreased
blood pressure at 12 weeks and six years. · Of the participants
who used substances (smoking, drinking, or drugs) at baseline, 67
percent at one year and 83 percent at six years significantly decreased
or stopped their use.
The
research began 22 years ago at UCSF through a federally funded adolescent
health training program. Mellin and colleagues sought to identify
a safe means of turning off the drive to overeat in obese youth,
a population for whom restrictive diets and weight loss drugs are
avoided. When the method was shown to be effective, the program
was adapted to adults. The program is described in Mellin's book,
The Solution: 6 Winning Ways to Permanent Weight Loss, (Regan Books
1998) and is being used in 150 hospital groups nationwide. Information
is also available on the Internet (www.weightsolution.com).
Mellin
suggests caution in response to these findings. "Larger scale
studies are needed to confirm these results," she said. "In
addition, pilot studies for the application of developmental skills
training to adult substance abuse and to school-based interventions
to prevent adult emotional and behavioral imbalance are planned."
Co-investigators
of the study are Mary Croughan-Minihane, PhD, UCSF associate professor
of family and community medicine and epidemiology and Larry Dickey,
MD, MSW, MPH, former UCSF assistant professor of family and community
medicine. The implications of this study may go beyond obesity treatment,
Mellin said, as the results show persistent changes in emotional
and behavioral balance, suggesting the possibility that the intervention
causes changes to the limbic brain.
The
limbic or "feeling" brain is thought to be the seat of
mammalian emotional and behavioral balance. The limbic brain is
programmed early in life and is more difficult to change in adulthood.
Traditional non-drug therapies for emotional and behavioral problems
do not change the limbic brain, a factor that limits their effectiveness.
The persistent, comprehensive changes shown in this study suggest
that developmental skills training may be a practical, clinical
means of altering the limbic brain and of treating depression and
other compulsive behaviors, Mellin said.
Recently
three UCSF psychiatric researchers postulated that limbic changes
might occur in adulthood through repeated contact with a responsive
environment, such as a loving relationship or long-term psychotherapy.
They wrote a book on the subject: A General Theory of Love, (Random
House, 2000). Practicing the skills of self-nurturing and effective
limit setting may create similar changes. According to Thomas Lewis,
MD, UCSF assistant clinical professor of psychiatry, and one of
the book's authors: "We know that the emotional parts of a
person's brain undergo substantial change as a direct result of
relationships with others. Mellin's study demonstrates the remarkably
powerful, long-lasting effects of limbic changes on mind and body."
The other authors of the book are Fari Amini, MD, UCSF professor
of psychiatry and Richard Lannon, MD, UCSF associate clinical professor
of psychiatry.
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