A team
of American and South Korean researchers conducted cell studies
that shed new light on the relative anti-cancer properties of green
and black tea.
The
evidence collected to date suggested that tea's proven anti-cancer
powers stem primarily from its powerfully antioxidant flavonoid-type
polyphenols.
Thus,
its been assumed that green and white tea must be the most
powerfully anti-cancer forms of the ancient beverage, since they
contains more flavonoid-type polyphenols than black tea does.
While
black tea (green tea oxidized by fermentation) contains between
3 and 10 percent water-soluble polyphenols by volume, green tea
boasts ten times that concentration.
However,
as we will see, polyphenols make up only part of the solids in tea:
and they may not be the sole or sufficient explanation for teas
well-documented anti-cancer properties.
And
green and black teas also contain different types and proportions
of polyphenols.
When
tea leaves ferment long enough to turn them black via oxidation,
the majority of their catechin-class flavonoid polyphenols change
into tannin-like flavonoids called theaflavins and theanine.
However,
some population studies have suggested that black tea is as or more
protective against certain cancers (including certain breast tumors)
as green tea.
Tea
flavonoids do five things that work together to stop cancer in its
early stages:
1. Cause programmed suicide (apoptosis) among cancer
cells.
2. Block P450 enzymes, which activate pro-cancer compounds.
3. Stop tumor-promoting chemical signals from cancer cells.
4. Disable damaged, cancer-promoting DNA
5. Block growth of new blood vessels in the tumor (angiogenesis)
Given
this context, the general thrust of what the USDA team found came
as no big surprise.
But
their unexpected findings vis a vis the effects of tea flavonoids
on human cancer cells is sure to send scientists back to the bench
for further exploration.
Black
and green tea work equally well; Benefits not tied tightly to flavonoid
content
The
joint USDA/South Korea team examined the ability of nine green tea
catechins, three black tea theaflavins, and theanine from black
tea to induce cell death (apoptosis) in isolated human cancer cells
(Friedman M et al 2006).
Tea,
berries, and other polyphenol-rich plants are considered key anti-cancer
agents because they undermine cancer when it is most vulnerable:
during its early, so-called promotion stage.
The
researchers reported that most of the flavanol-type flavonoids in
both green and black tea -- catechins, theaflavins, and theanine
cut the numbers of cancerous human breast, colon, liver,
and prostate cells, without big differences among them.
However
the efficacy of each different extract of black or green tea tested
depended not on its flavonoid content, but simply on the sheer amount
of dissolved solids per volume of liquid, regardless of their flavonoid
content.
This
suggests that something about the non-flavonoid compounds play key
roles, and that therefore, black tea may offer anti-cancer benefits
closer to those of green and white tea than thought.
They
also found that ethanol/water extracts of tea possess more flavonoids
and are more potently anti-cancer, suggesting that tea supplements
(mostly made this way) may have a bit of an edge over water extracts,
such as plain cups of tea. But any hypothetical anti-tumor advantage
supplemental tea capsules might offer is likely to be quite expensive,
compared with enjoying tea by the cup.
As
the USDA/Korea team said (Friedman M et al 2006), their findings
extend our knowledge of the anti-cancer potential of tea, and suggest,
most significantly, that consumers may benefit more
by drinking both green and black teas.
Editor's
note:
We
consider organic whole foods from both plant and animal kingdoms
to be a major key to superior health. We also think it's terribly
important to eat fish at least twice a week to get the essential
fatty acids. Here at our house, we only eat wild Alaskan salmon
and other wild seafoods from our friends at Vital Choice.
Click
here to visit Vital Choice Seafood.
Sources:
Friedman
M et al. Structure-Activity Relationships of Tea Compounds against
Human Cancer Cells. J Agric Food Chem. Published on-line ahead of
print, December 16, 2006: ASAP Article doi: 10.1021/jf062276h S0021-8561(06)02276-X.
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